evaluation of copper, zinc, cu/zn, and vegf in patients with aml in iran
نویسندگان
چکیده
background: copper and zinc are the elements with numerous physiological activities. copper (cu) has an important role in angiogenesis and acts by increasing vascular endothelial growth factor (vegf). serum levels of copper will be increased in cancer incidence, progression and recurrence. the aim of this study was to measure blood levels of copper, zinc, and the ratio of cu /zn, as well as vegf levels before and after treatment of acute myeloid leukemia. methods: thirty patients who were recently diagnosed with acute myeloblastic leukemia (aml) in shahid ghazi tabatabai oncology hospital enrolled in this clinical trial. on the first day, blood samples were taken for copper, zinc, and vegf assay and flowcytometry. treatment protocol was (7×3) regimen. blood samples were collected for evaluation of copper, zinc, and vegf. they were sent to biochemistry laboratory in medicine faculty for analysis. results: amongst 30 aml patients, 14 (46.7%) were female and 16 (53.3%) were male. patients of various ages ranged from 16 to 53 years, with a median age of 9.1±9.35 years. the mean serum level of copper, zinc, and mean cu/zn ratio before and after treatment showed significant difference (p<0.05) there was also significant difference between the mean vegf level before and after treatment (p<0.05). conclusion: this study reveals that there is no significant relationship between copper, zinc serum levels, their ratio, and vegf in aml patients. we hypothesize that increased serum copper is associated with increase of vegf levels which can indicate the impact of copper in malignancies including aml.
منابع مشابه
Evaluation of Copper, Zinc, Cu/Zn, and VEGF in Patients with AML in Iran
BACKGROUND Copper and zinc are the elements with numerous physiological activities. Copper (Cu) has an important role in angiogenesis and acts by increasing Vascular Endothelial Growth Factor (VEGF). Serum levels of copper will be increased in cancer incidence, progression and recurrence. The aim of this study was to measure blood levels of copper, zinc, and the ratio of Cu /Zn, as well as VEGF...
متن کاملrole of cultural iran in promotion of multilaieralism in central asia and caucasus
cultural iran is a scope that is more extended than the political territories of iran as a political unit. this concept means that cultural geography(mehdi moghanlo-1383-1) of iran is greater than its political geography which, according to history, has a long history extending west-east from kandahar to the euphrates and north-south from the persian gulf to the caucasus including transoxiana a...
15 صفحه اولec adoption and critical success factors of ec in smes in iran
تجارت الکترونیکی شیوه اجرای مسئولیتها، تقابل با مشتریان و امور معمول عملیاتی در شرکتها را تغییر داده است. تجارت الکترونیکی در عمل تنها خرید و فروش کالاها را از طریق ابزار الکترونیک نمی باشد، بلکه تمام فعالیتهای لازم جهت انجام فرایند فروش را نیز در بر میگیرد. در اواخر دهه 1990 بسیاری از شرکتها فعالیتهای خود را به منظور دستیابی به مشتریان جدید و یا ارائه فرصتهای جدید به مشتریان موجود گسترش دادند...
analyzing patterns of classroom interaction in efl classrooms in iran
با به کار گیری روش گفتما ن شنا سی در تحقیق حا ضر گفتا ر میا ن آموزگا را ن و زبا ن آموزا ن در کلا سهای زبا ن انگلیسی در ایرا ن مورد بررسی قرار گرفت. ا هداف تحقیق عبا رت بودند از: الف) شنا سا ئی سا ختارهای ارتبا ط گفتا ری میا ن معلمین و زبا ن آموزا ن ب) بررسی تا ثیر نقش جنسیت دبیرا ن و زبا ن آموزان بر سا ختا رهای ارتبا ط گفتا ری میا ن آنها پ) مشخص کردن اینکه آ یا آموزگاران غا لب بر این ارتبا ط گف...
منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of cancer preventionجلد ۴، شماره ۴، صفحات ۱۵۱-۱۵۳
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023